FIELD: medicine.
SUBSTANCE: invention relates to a dipeptidyl ketoamide m-methoxyphenyl derivative of the formula II, where R1a is selected from a group consisting of C1-C6 alkyl and C3-C6 cycloalkyl, R2a is selected from a group consisting of H and C1-C6 alkyl, R3a is C3-C6 cycloalkyl or methoxy, provided that, when R3a is methoxy, R1a is cyclopropyl, and R2a is H, or its pharmaceutically acceptable salt or stereoisomer, which can be used for the treatment of diseases and conditions associated with increased calpain activity, such as heart damage caused by infarction, ischemia with or without reperfusion, neurodegenerative disorders, malaria, diabetic nephropathy, HIV virus-induced neurotoxicity, malignant tumor, and fibrotic diseases.
EFFECT: obtainment of a dipeptidyl ketoamide m-methoxyphenyl derivative for use in medicine.
16 cl, 6 ex
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