FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to obstetrics and gynecology. In the peripheral venous blood of pregnant women with threatened early miscarriage, 5–12 weeks before the start of maintenance therapy, the content of CD163+ cells in the gate of alternatively activated CD14+CD16++ monocytes is determined, and if its value is 15.6% or more, reproductive losses are predicted in the form of a non-developing pregnancy and spontaneous miscarriage before 22 weeks of gestation.
EFFECT: method makes it possible to increase the accuracy of predicting reproductive losses in the form of spontaneous miscarriage and non-developing pregnancy at gestational age up to 22 weeks by determining the content of CD163+ alternatively activated monocytes in peripheral blood, which are a marker of the inflammatory process and impaired immune homeostasis leading to spontaneous miscarriage.
1 cl, 1 tbl, 3 ex
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