METHOD FOR OBTAINING SPIRULINA BIOMASS WITH A HIGH CONTENT OF BIOLOGICALLY ACTIVE COMPOUNDS Russian patent published in 2023 - IPC C12N1/12 C12P23/00 C12R1/89 

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology. A method for obtaining Arthrospira (Spirulina) platensis spirulina biomass is proposed, including preparation of A. (S.) platensis inoculum and flow cultivation of A. (S.) platensis on a Zarruk nutrient medium in two plane-parallel photobioreactors at 33-35°C and illumination of 20 klx s specific flow rate 0.1-0.2 day-1 in the two-stage chemostat mode. In the first photobioreactor, A. (S.) platensis biomass is accumulated until the stationary growth phase is reached; on the 8-10th day, the culture is transferred to the flow mode of cultivation; at the same time, part of the working volume is transferred from the first photobioreactor to the second one; daily from the second photobioreactor, a part of the working volume is withdrawn for harvest, which is restored by a part of the worker from the first photobioreactor, and the working volume in the first photobioreactor is restored by adding fresh nutrient medium.

EFFECT: increased yield of A. (S.) platensis biomass with high content of biologically active compounds - C-phycocyanin, lipids and fatty acids.

2 cl, 2 dwg, 1 tbl, 2 ex