PROCESS FOR OBTAINING COLLAGEN GEL FOR USE IN MEDICINE AND COSMETOLOGY Russian patent published in 2023 - IPC A23J1/10 

FIELD: biotechnology.

SUBSTANCE: invention proposes a process for obtaining a collagen gel including the isolation of type 1 collagen from the tendons of rat tails. At the same time, tendons extracted from rat tails are extracted in 0.5 M acetic acid for 30 days at a temperature of 4°C. The resulting solution is centrifuged for 10 min at 5000 g and the collagen solution is isolated from the undissolved tendons at a collagen concentration in the solution of at least 1 mg/ml. 3 ml of the resulting collagen solution is added to a Petri dish, to which 0.8 ml of 10-fold M 199 medium and concentrated ammonia solution are added to adjust pH to 7.0-7.2 and incubated for 5 minutes. The resulting collagen gel is washed with distilled water.

EFFECT: invention provides obtaining a collagen gel of a dense structure.

1 cl, 4 dwg, 2 ex