METHOD FOR PREDICTING THE RISK OF SEVERE COVID-19 IN A PATIENT Russian patent published in 2023 - IPC G01N33/48 C12Q1/6827 C12Q1/6883 C12N15/11 G16B20/20 G16H50/30 

FIELD: medicine.

SUBSTANCE: it can be used to predict the risk of severe COVID-19 in a patient. Blood is taken for whole genome sequencing. Risk alleles for severe COVID-19 are identified. The coefficients of single nucleotide polymorphisms (SNPs) from Table 2 are summed with the risk alleles identified in the patient for severe COVID-19 according to the formula:

,

where g_i is the number of risk alleles for severe COVID-19, β_i is the SNP factor from table 2, β_age is the regression coefficient for the age variable equal to 0.02, β₀ is the coefficient 0.48 for women or 0.71 for men, exp is the exponential function. If the value obtained is less than 0.5, a mild course of the disease is predicted. If the value obtained is greater than 0.5, a severe course of the disease is predicted.

EFFECT: method provides an effective prediction of the risk of developing a severe course of COVID-19 by using the original calculation formula.

1 cl, 2 dwg, 3 tbl, 2 ex