METHOD FOR PRODUCTION OF L-LYSIN BY MODIFYING ACONITASE GENE AND/OR ITS REGULATIVE ELEMENTS Russian patent published in 2023 - IPC C12N15/70 C12N1/21 C12N9/88 C12P13/08 

Abstract RU 2792116 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to a method for the production of L-lysin by fermentation. The method provides modification of an aconitase gene and/or its regulative element in a bacterium chromosome in such a way that activity and/or an aconitase expression level of the bacterium are reduced, but not eliminated, and production of L-lysin by fermentation in the bacterium obtained using the specified modification.

EFFECT: invention provides an increase in the yield of L-lysin.

1 cl, 3 tbl, 5 ex

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RU 2 792 116 C2

Authors

Ma Jiyin

Wen Tingyi

Chen Jinlong

Liang Yong

Liu Shuwen

Wei Aiying

Yang Lipeng

Ren Rui

Meng Gang

Zhao Chunguang

Zhang Yun

Shang Xiuling

Guo Xiaowei

Dates

2023-03-16Published

2014-01-07Filed