METHOD FOR INTRODUCING RADIOPAQUE SUBSTANCES INTO THE BODY OF LABORATORY RODENTS FOR INTRAVITAL RADIATION IMAGING OF INTERNAL ORGANS TO ASSESS THE GROWTH DYNAMICS OF MALIGNANT ORGANOTROPIC NEOPLASMS IN EXPERIMENTAL ONCOLOGY Russian patent published in 2023 - IPC G09B23/28 A61B6/02 

FIELD: medicine.

SUBSTANCE: invention relates to experimental oncology, and can be used for intravital radiation imaging of malignant neoplasms of internal organs. In experimental animals at the stage of drug-induced sleep, access is provided to the peripheral vein — the tail, in the middle part of which an intravenous cannula is installed with a contrast flow rate of 17 ml/min and an infusion system is connected to control the flow of radiopaque substance. Next, the test animal is introduced into the gantry of a computed tomograph, then the radiopaque substance is supplied at a rate of 0.25 ml/min, and the area of interest is scanned.

EFFECT: method makes it possible to assess the accumulation of a contrast agent in areas of interest and/or pathological foci without disturbing the basic physiological parameters of the vital activity of the body of a laboratory animal due to a lower concentration and higher fluidity of the contrast agent used.

1 cl, 4 dwg