FIELD: medicine.
SUBSTANCE: invention relates to a method for the treatment of bladder cancer, including having the REF STING allele, the WT STING allele, the AQ STING allele or the HAQ STING allele, including the administration to a patient in need of treatment of an effective amount of Compound 1 or its pharmaceutically acceptable salt or a pharmaceutical composition containing Compound 1 or its pharmaceutically acceptable salt, as well as to the use of Compound 1 or its pharmaceutically acceptable salt for the preparation of a pharmaceutical composition for the treatment of bladder cancer.
EFFECT: treatment of bladder cancer, which makes it possible to avoid or delay radical cystectomy.
(Connection 1)
17 cl, 13 dwg, 7 tbl, 112 ex
Title | Year | Author | Number |
---|---|---|---|
ANTIBODY-STING AGONIST CONJUGATES AND USE THEREOF IN IMMUNOTHERAPY | 2020 |
|
RU2826228C2 |
3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ZINC FINGER PROTEIN 2 (IKZF2) OF THE IKAROS FAMILY | 2019 |
|
RU2797559C2 |
3-(5-AMINO-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USE THEREOF IN TREATING DISEASES ASSOCIATED WITH ZINC FINGER PROTEIN 2 OF IKAROS (IKZF2) FAMILY | 2019 |
|
RU2815714C2 |
UREA-BASED COMPOUNDS AND COMPOSITIONS BASED ON THEM AS SMARCA2/BRM ATPASE INHIBITORS | 2019 |
|
RU2798462C2 |
CONJUGATE OF ANTI-CLAUDIN ANTIBODY AND MEDICINAL AGENT AND PHARMACEUTICAL USE THEREOF | 2020 |
|
RU2826119C1 |
SULFOMALEIMIDE-BASED LINKERS AND CORRESPONDING CONJUGATES | 2019 |
|
RU2815199C2 |
PYRIMIDINE COMPOUND OR ITS SALT | 2020 |
|
RU2787992C1 |
MAITANZINOID DERIVATIVES WITH SELF-SPLITTING PEPTIDE LINKERS AND THEIR CONJUGATES | 2018 |
|
RU2765098C2 |
ANTIBODY TO B7H3-EXATECAN ANALOGUE CONJUGATE AND ITS USE IN MEDICINE | 2019 |
|
RU2785664C2 |
DERIVATIVES OF BENZISOXAZOLESULFONAMIDE | 2020 |
|
RU2813356C2 |
Authors
Dates
2023-05-02—Published
2019-05-31—Filed