FIELD: medicine.
SUBSTANCE: invention relates to neurology, and can be used to detect a high risk of severe brain damage in newborns with hypoxic-ischemic lesions of the central nervous system. The level of protein S-100 and the level of neuron-specific enolase in the child's blood serum are determined. The study is carried out twice on the fifth and on the twenty-second day of a child's life, the dynamics of the S-100 protein level and the level of neuron-specific enolase in the blood serum are compared. An increase in the level of S-100 protein by 10% or more in the second study, combined with the absence of changes in the level of neuron-specific enolase from the initial values, reveals a high risk of severe brain damage in newborns with hypoxic-ischemic lesions of the central nervous system. In case of any other result the risk is low.
EFFECT: method enables early detection among newborns with hypoxic-ischemic lesions of the central nervous system of children with a high risk of severe brain damage requiring special treatment by determining the level of S-100 protein and the level of neuron-specific enolase in the blood.
1 cl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR PREDICTION OF RISK OF SEVERE NEONATAL NERVOUS SYSTEM INVOLVEMENT IN NEW-BORNS OF VARIOUS GESTATIONS | 2012 |
|
RU2528907C2 |
METHOD FOR PREVENTION OF PERINATAL CENTRAL NERVOUS SYSTEM DAMAGE IN NEWBORN INFANTS | 2012 |
|
RU2517162C2 |
METHOD OF EARLY DIAGNOSTICS OF PERINATAL AFFECTION OF CNS IN FULL-TERM NEWBORN BABIES | 2009 |
|
RU2404432C1 |
METHOD FOR PREDICTION OF DEGREE OF SEVERITY OF HYPOXIC PERINATAL CNS DAMAGE IN NEWBORNS | 2011 |
|
RU2463603C1 |
METHOD OF DIAGNOSTICS OF THE DEGREE OF NEUROLOGIC IMPAIRMENT INTENSITY IN YOUNG CHILDREN | 2017 |
|
RU2668528C1 |
METHOD FOR FORECASTING NEUROLOGIC DISORDERS IN NEWBORNS WITH DELAY OF INTERNAL DEVELOPMENT OF FRUIT | 2016 |
|
RU2629395C1 |
METHOD FOR PREDICTION OF PERINATAL LESIONS OF THE CENTRAL NERVOUS SYSTEM IN TERM NEWBORN | 2022 |
|
RU2782800C1 |
LABORATORY DIAGNOSTIC TECHNIQUE FOR SEPTIC ENCEPHALOPATHY IN NEWBORNS SUFFERING FROM PERINATAL HYPOXIC INJURY OF CENTRAL NERVOUS SYSTEM | 2012 |
|
RU2519729C1 |
METHOD FOR PREDICTING THE FLOW OF NEUROLOGICAL DISORDERS IN EARLY-AGED CHILDREN AT PERINATAL LESION OF CENTRAL NERVOUS SYSTEM (CNS) | 2005 |
|
RU2286575C1 |
METHOD FOR PREDICTION OF PERINATAL CENTRAL NERVOUS SYSTEM INJURY IN PREMATURE NEWBORNS | 2014 |
|
RU2568914C1 |
Authors
Dates
2023-05-15—Published
2022-03-03—Filed