METHOD FOR PREDICTING THE FLOW OF NEUROLOGICAL DISORDERS IN EARLY-AGED CHILDREN AT PERINATAL LESION OF CENTRAL NERVOUS SYSTEM (CNS) Russian patent published in 2006 - IPC G01N33/53 G01N33/50 

FIELD: medicine, pediatrics.

SUBSTANCE: in neonatal's blood serum one should detect neurospecific enolase and homocarnosine to calculate the following prognostic coefficient: P = 0.328 × HC + 0.0004 × NSE² - 0.041 × NSE + 0.604, where NSE - neurospecific enolase (ng/m), HC - homocarnosine (nM/m). If the value of calculated prognostic coefficient is under 0.54 one should predict favorable flow of the disease at the background of standard basic therapy at unobserved symptomatics to the end of the 1^st yr of life. In case if the coefficient is above 0.54 it is possible to predict unfavorable flow of the disease mentioned. For implementation of the present method one should require sufficiently small quantity of serum. The method provides high sensitivity and diagnostic accuracy.

EFFECT: higher accuracy and efficiency of prediction.

2 ex, 1 tbl