2,6-DIMETHYL-N-((PYRIDIN-4-YL)METHYL)IMIDAZO[1,2-B]PYRIDAZIN-8-AMINE AND 2,5-DIMETHYL-N-[(PYRIDIN-4-YL)METHYL DERIVATIVES ]PYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE FOR THE TREATMENT OF VIRAL INFECTIONS Russian patent published in 2023 - IPC C07D487/04 A61K31/5025 A61K31/519 A61P31/12 A61P31/14 A61P31/16 

Abstract RU 2798107 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound having formula (I) or a pharmaceutically acceptable salt thereof, where one of X and Y is C and the other is N; R1 is selected from halogen, CN, C1-C4 alkoxy, and C1-C4 alkyl optionally substituted with 1-3 halogens; and R2 is 3,4-dimethoxyphenyl or 1,3-dimethyl-1H-indazol-5-yl. The invention also relates to a pharmaceutical composition for inhibiting enteroviruses based on a compound of formula (I).

EFFECT: new compounds and a pharmaceutical composition based on them have been obtained, which can be used in medicine as effective medicinal products for the treatment of enterovirus infection, where enteroviruses are selected from EV, Coxsackie virus, poliomyelitis, and rhinovirus.

18 cl, 7 tbl, 9 ex

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RU 2 798 107 C2

Authors

Westman, Jacob

Dates

2023-06-15Published

2019-08-20Filed