METHOD OF PREVENTION OF POSTOPERATIVE PANCREATIC FISTULA DURING RESECTION INTERVENTIONS ON THE PANCREAS Russian patent published in 2023 - IPC A61K9/00 A61K35/39 A61K31/573 A61K35/42 A61P1/00 

FIELD: medicine; surgery; gastroenterology.

SUBSTANCE: invention can be used to prevent postoperative pancreatic fistula during resection interventions on the pancreas. To do this, 10 days before the planned surgical intervention, the patient is administered the drug Creon 25000, orally, at a dose of 50,000 IU, during meals, 3 times a day. On the day of the surgery, 2 hours before it begins, prednisolone 60 mg intravenously, octreotide 300 μg subcutaneously, aprotex 200,000 ATP intravenously by drip are administered. The administration of prednisolone and octreotide is continued at the same dose every 8 hours for 3 days. Aprotex is administered for 2 days after surgery at a dose of 100,000 ATP per day, intravenously.

EFFECT: invention provides prevention of postoperative pancreatic fistula due to preoperative enzyme replacement therapy, perioperative drug blockade of pancreatic function, as well as prevention of inflammatory reactions.

1 cl, 2 ex