FIELD: biotechnology and medicine.
SUBSTANCE: method for producing a hemostatic drug in the form of an aerogel based on bacterial cellulose and alginate, used to achieve a rapid hemostatic effect. Invention includes obtaining a biocomposite based on oxidized bacterial cellulose obtained by cultivating the producer Komagataeibacter sucrofermentans H-110 (VKPM-11267), calcium alginate, thrombin or factor X blood coagulation or thrombin and sodium fusidine, and obtaining an aerogel, the biocomposite is frozen in a low-temperature refrigerator for 1 day, after which it is freeze-dried.
EFFECT: hemostatic drug in the form of an aerogel based on oxidized bacterial cellulose and calcium alginate, which is able to stop bleeding within 60-120 seconds.
4 cl, 4 ex
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Authors
Dates
2023-06-28—Published
2022-10-07—Filed