TRIPHENYLPHOSPHONIUM TETRAPEPTIDE DERIVATIVES WITH ANTIOXIDANT ACTIVITY Russian patent published in 2023 - IPC C07K5/107 A61K38/07 A61P39/06 

Abstract RU 2799310 C1

FIELD: chemistry of peptide compounds.

SUBSTANCE: invention relates to chemically modified peptides with antioxidant activity. The essence of the claimed technical solution is derivatives of the synthetic tetrapeptide Tyr-DArg-Phe-Lys, modified with a TPP group, with a linker length of three to five carbon atoms which have antioxidant activity against living cells, primarily human cells.

EFFECT: invention can be used in various fields of medicine, veterinary medicine and pharmacy, for example, to inhibit the level of reactive oxygen species in cells.

1 cl, 4 dwg, 4 ex

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RU 2 799 310 C1

Authors

Abdullin Timur Ildarovich

Ishkaeva Rezeda Anasovna

Kamalov Marat Iliasovich

Garifullin Ruslan Ildarovich

Salakhieva Diana Vitalevna

Laikov Aleksandr Vladimirovich

Dates

2023-07-04Published

2022-12-23Filed