FIELD: medicine.
SUBSTANCE: invention concerns the use of cationic tetrapeptide Phe-D-Arg-Phe-Lys-NH2 as mitochondrial synthase inhibitor of nitrogen oxide.
EFFECT: invention provides better compared with prototype (“Unitiol”) survival rate of experimental animals with cerebrovascular disorders, later onset of cramps and considerable increase in life expectancy of experimental animals in hypercapnic hypoxia.
1 cl, 3 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| CATIONIC ETHER OF L-NITROARGININE CATIONIC TYPE AS INHIBITOR OF MITOCHONDRIAL SYNTHASE OF NITROGEN OXIDE | 2015 |
|
RU2600159C1 |
| METHOD FOR REDUCTION OF OXIDISING INJURY (VERSIONS) | 2005 |
|
RU2376028C2 |
| TRIPHENYLPHOSPHONIUM TETRAPEPTIDE DERIVATIVES WITH ANTIOXIDANT ACTIVITY | 2022 |
|
RU2799310C1 |
| MODIFIED MITOCHONDRIA AND THEIR USE | 2019 |
|
RU2811467C2 |
| MITOCHONDRIAL DNA LESIONS BEING THE SIGN OF ATHEROSCLEROTIC ISCHEMIC CARDIAC DISEASE | 2000 |
|
RU2243558C2 |
| MEDICATION FOR TREATMENT OF HYPOXIC AND TOXIC MITOCHONDRIAL DYSFUNCTIONS AND METHOD OF ITS OBTAINING | 2008 |
|
RU2405558C2 |
| DPP3-BINDING MOLECULE AIMED AT SPECIFIC DPP3 EPITOPES AND BINDING TO THEM AND ITS USE FOR PREVENTION OR TREATMENT OF DISEASES/ACUTE CONDITIONS, WHICH ARE RELATED TO OXIDATIVE STRESS | 2018 |
|
RU2787033C2 |
| PEPTIDE COMPOUND RECOVERING FUNCTION OF MYOCARDIUM | 2004 |
|
RU2255756C1 |
| RECOMBINANT YEAST CELLS PRODUCING POLYLACTIC ACID AND THEIR USE | 2016 |
|
RU2758138C2 |
| METHOD FOR DETECTING RED BLOOD CELL FUNCTION OF NITRIC OXIDE GENERATION | 2014 |
|
RU2568838C1 |
