METHOD FOR MAKING (2E,2'E)-2,2'-(1,2,4-THIADIAZOLE-3,5-DIYL)BIS[3-ARYL(HETARYL)ACRYLONITRILES] Russian patent published in 2023 - IPC C07D285/08 C07D417/14 

Abstract RU 2802632 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a method for obtaining (2E,2' E) -2.2' -(1,2,4-thiadiazol-3,5-diyl)bis[3-aryl(hetaryl)acrylonitriles] of general formula 1, where Ar = 2-(trifluoromethyl)phenyl, 4-ethylphenyl, 2-bromophenyl, 5- methyl-2-furyl, 3,4-bis(benzyloxy)phenyl or 3,4,5-trimethoxyphenyl. The method includes carrying out the reaction of (E)-3-aryl(hetaryl)-2-cyanoprop-2-entioamides with a twofold molar excess of bromine in an N,N-dimethylformamide medium.

EFFECT: increased yields of target products, no toxic, flammable or foul-smelling by-products.

1 cl, 6 ex

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RU 2 802 632 C1

Authors

Krivokolysko Bogdan Sergeevich

Pakholka Nikolai Aleksandrovich

Krivokolysko Sergei Gennadievich

Dakhno Polina Grigorevna

Dotsenko Viktor Viktorovich

Strelkov Vladimir Denisovich

Dates

2023-08-30Published

2022-12-06Filed