DP ANTAGONIST Russian patent published in 2023 - IPC C07C235/56 C07C327/48 C07D309/06 A61K31/196 A61K31/216 A61K31/351 A61P25/00 A61P25/18 A61P25/20 

Abstract RU 2803243 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a DP receptor antagonist which is a compound of general formula (I), where R1, R2 -R6, R11, R12, L, J, m, n are defined in the claims, or a pharmaceutically acceptable salt thereof. The compounds are highly safe and can be used as active pharmaceutical ingredients in DP receptor mediated diseases.

EFFECT: compound represented by the general formula (I) and a pharmaceutically acceptable salt thereof also have a good ability to penetrate into the central nervous system, and thus are particularly useful as a prophylactic and/or therapeutic agent for diseases associated with DP receptors present in the central nervous system, in particular disturbances in sleep and wakefulness.

14 cl, 2 tbl, 22 ex

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RU 2 803 243 C2

Authors

Asada, Masaki

Hanada, Keisuke

Higuchi, Satonori

Naganawa, Atsushi

Takeda, Yasuhiro

Dates

2023-09-11Published

2019-09-19Filed