METHOD OF PRECLINICAL DIAGNOSIS OF FIBROSIS IN PATIENTS WITH POSTMASTECTOMY SYNDROME Russian patent published in 2023 - IPC G01N33/50 A61B5/00 

Abstract RU 2804898 C1

FIELD: medicine; laboratory diagnostics.

SUBSTANCE: invention can be used for preclinical assessment of fibrosis in patients with postmastectomy syndrome. The levels of hyaluronic acid and N-terminal propeptide of procollagen III in blood serum is determined by enzyme immunoassay. If the level of hyaluronic acid is above 11.9 ng/ml and the level of the N-terminal propeptide of procollagen III is above 16.5 ng/ml, soft tissue fibrosis is diagnosed.

EFFECT: method provides objectivity of diagnostics, allows to identify soft tissue fibrosis at the preclinical stage by quantitative analysis of the level of fibrosis molecules in blood serum.

1 cl, 2 ex

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RU 2 804 898 C1

Authors

Pospelova Mariia Lvovna

Krasnikova Varvara Valerevna

Fionik Olga Vladimirovna

Kaiumova Evgeniia Evgenevna

Samochernykh Konstantin Aleksandrovich

Vasileva Elena Iurevna

Makhanova Albina Mansurovna

Nikolaeva Aleksandra Ernstovna

Tonian Samvel Nikolaevich

Krasnopeev Iurii Ivanovich

Dates

2023-10-09Published

2023-05-26Filed