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(19)

(11)

2 770 411

(13)

(51)

IPC

C07K16/28(2006-01-01)

C07K16/30(2006-01-01)

A61K39/395(2006-01-01)

C12N5/783(2010-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2018116582, 2018-05-04

(24)

Start date

2013-09-18

(22)

Actual filing date

2018-05-04

(45)

Published

2022-04-15

(72)

Inventor

Orentas Rimas Dzh.Pastan, Ira, Kh.Dimitrov Dimiter S.Makkoll Kristal L.

(73)

Holder

The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

CHIMERIC ANTIGEN RECEPTORS M971 Russian patent published in 2022 - IPC C07K16/28 C07K16/30 A61K39/395 C12N5/783 A61P35/00

Abstract RU 2770411 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to a pharmaceutical composition comprising an effective amount of T cells and a pharmaceutically acceptable carrier, wherein the T cells comprise a recombinant expression vector or nucleic acid, which contain a nucleotide sequence coding a chimeric antigen receptor (CAR).

EFFECT: invention is effective for treating or preventing cancer expressing CD22 in a mammal.

50 cl, 6 dwg, 2 tbl, 7 ex

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RU 2 770 411 C1

Authors

Orentas Rimas Dzh.

Pastan, Ira, Kh.

Dimitrov Dimiter S.

Makkoll Kristal L.

Dates

2022-04-15—Published

2018-05-04—Filed