Show metadata Hide metadata

(19)

(11)

2 770 411

(13)

(51)

IPC

C07K16/28(2006-01-01)

C07K16/30(2006-01-01)

A61K39/395(2006-01-01)

C12N5/783(2010-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2018116582, 2018-05-04

(24)

Start date

2013-09-18

(22)

Actual filing date

2018-05-04

(45)

Published

2022-04-15

(72)

Inventor

Orentas Rimas Dzh.Pastan, Ira, Kh.Dimitrov Dimiter S.Makkoll Kristal L.

(73)

Holder

The United States Of America, As Represented By The Secretary, Department Of Health And Human Services

CHIMERIC ANTIGEN RECEPTORS M971 Russian patent published in 2022 - IPC C07K16/28 C07K16/30 A61K39/395 C12N5/783 A61P35/00

Abstract RU 2770411 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to a pharmaceutical composition comprising an effective amount of T cells and a pharmaceutically acceptable carrier, wherein the T cells comprise a recombinant expression vector or nucleic acid, which contain a nucleotide sequence coding a chimeric antigen receptor (CAR).

EFFECT: invention is effective for treating or preventing cancer expressing CD22 in a mammal.

50 cl, 6 dwg, 2 tbl, 7 ex

Similar patents RU2770411C1

Title	Year	Author	Number
GLYCAN-DEPENDENT IMMUNOTHERAPY MOLECULES	2016	Demetriou Majkl Chzhou Rejmond Venkhou	RU2754661C2
COMPOSITIONS AND METHODS FOR SELECTIVE PROTEIN EXPRESSION	2017	Golosov, Andrei Guimaraes, Carla Motz, Gregory Milone, Michael Ellebrecht, Christoph, T. Payne, Aimee, S.	RU2795467C2
CHIMERIC ANTIGEN RECEPTORS TARGETED B-CELL MATURATION ANTIGEN	2013	Kokhenderfer Dzhejms Nobl	RU2766608C2
CHIMERIC ANTIGENIC (CAR) RECEPTOR AGAINST CD123 FOR USE IN TREATING MALIGNANT TUMORS	2015	Brogdon, Jennifer Gill, Saar Glass, David Kenderian, Saad Loew, Andreas Mannick, Joan Milone, Michael Murphy, Leon Porter, David, L. Ruella, Marco Wang, Yongqiang Wu, Qilong Zhang, Jiquan	RU2724999C2
TREATMENT OF MALIGNANT NEOPLASM USING HUMANIZED CHIMERIC ANTIGEN RECEPTOR AGAINST BCMA	2015	Brogdon, Jennifer Choi, Eugene Ebersbach, Hilmar Glass, David Huet, Heather June, Carl, H. Mannick, Joan Milone, Michael, C. Murphy, Leon Plesa, Gabriela Richardson, Celeste Ruella, Marco Singh, Reshma Wang, Yongqiang Wu, Qilong	RU2751660C2
METHODS FOR PRODUCING CELLS EXPRESSING CHIMERIC ANTIGEN RECEPTOR	2015	Bedoya Felipe Ghassemi Saba June Carl H. Levine Bruce L. Melenhorst Jan J. Milone Michael C. Powell Daniel J. Jr. Zheng Zoe	RU2751362C2
CD20 THERAPY, CD22 THERAPY AND COMBINATION THERAPY WITH CELLS EXPRESSING CHIMERIC ANTIGEN RECEPTOR (CAR) K CD19	2016	Bitter, Hans Bordeaux,Jennifer, Mary Brannetti, Barbara Brogdon, Jennifer Dakappagari, Naveen, Kumar Gill, Saar Highfill, Steven Huang, Lu June, Carl, H. Kim, Ju, Young Lei, Ming Li, Na Loew, Andreas Orlando, Elena Ruella, Marco Tran, Thai Zhahg, Jimin Zhou, Li	RU2752918C2
CELL	2015	Pyule Marten Kordoba Shon Onuokha Simobi Tomas Sajmon	RU2768019C2
TREATING CANCER USING A CHIMERIC ANTIGENIC CLL-1 RECEPTOR	2015	Brogdon, Jennifer Ebersbach, Hilmar Gill, Saar Glass, David Jascur, Julia Kenderian, Saad Mannick, Joan Milone, Michael, C. Murphy, Leon Richardson, Celeste Singh, Reshma Wei, Lai Wu, Qilong Yang, Qiumei Zhang, Jiquan	RU2741120C2
CHIMERIC HUMAN MESOTHELIOGEN ANTIGEN RECEPTORS AND USE THEREOF	2014	Bitti Gregori Engels Boris Idamakanti Neeradzha Dzhun Karl Kh. Lev Andreas Sun Khuejtszyuan U Tsilun	RU2714902C2

RU 2 770 411 C1

Authors

Orentas Rimas Dzh.

Pastan, Ira, Kh.

Dimitrov Dimiter S.

Makkoll Kristal L.

Dates

2022-04-15—Published

2018-05-04—Filed