APPLICATION OF 3-AROYL-4-[2-(HYDROXYMETHYL)-PHENYLAMINO]-6',6'-DIMETHYL-1'-(3-FLUOROPHENYL)-6',7'-DIHYDRO-5H-SPIRO[FURAN-2, 3'-INDOLE]-2',4',5(1'H,5'H)-TRIONES AS AGENT WITH ANTIOXIDANT ACTIVITY Russian patent published in 2023 - IPC C07D491/107 A61K31/407 A61P17/18 

Abstract RU 2806189 C1

FIELD: organic chemistry.

SUBSTANCE: invention relates to 3-aroyl-4-[2-(hydroxymethyl)-phenylamino]-6',6'-dimethyl-1'-(3-fluorophenyl)-6',7'-dihydro-5H-spiro[furan- 2,3'-indole]-2',4',5(1'H,5'H)-triones of the general formula:

,

where Ar = 4-BrC6H4 (a); Ar = 4-ClC6H4 (b).

EFFECT: new -aroyl-4-[2-(hydroxymethyl)-phenylamino]-6',6'-dimethyl-1'-(3-fluorophenyl)-6',7'-dihydro-5H-spiro[furan -2,3'-indole]-2',4',5(1'H,5'H)-triones have been obtained with antioxidant activity, which can be used in pharmacology and medicine as an antioxidant agent.

1 cl, 3 ex, 1 tbl

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RU 2 806 189 C1

Authors

Maslivets Anna Andreevna

Maslivets Andrei Nikolaevich

Dates

2023-10-27Published

2023-03-20Filed