FIELD: organic chemistry.
SUBSTANCE: invention can be used to obtain 5-hydroxy-6-methyluracil (oxymethacyl, Immureg) — an immunostimulant with a wide spectrum of pharmacological activity. A method has been proposed for the production of 5-hydroxy-6-methyluracil by oxidation of 6-methyluracil in an alkaline medium at a temperature of 60–70°C with subsequent release of 6-methyluracil-5-sulfate and hydrolysis of the latter with sulfuric acid at 80–85°C, characterized by the oxidation process of 6-methyluracil carried out with continuous bubbling of air through the reaction mixture for 6 hours, while the oxidation of 6-methyluracil occurs with two oxidizing agents: ammonium or potassium or sodium persulfate and hydrogen peroxide.
EFFECT: increase of the yield of the target product.
1 cl, 4 tbl, 2 ex
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