NICOTINE-CONTAINING PRODUCT FOR ORAL USE WITH pH REGULATING AGENT Russian patent published in 2023 - IPC A24B13/00 

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a packaged product with nicotine for oral use. The article contains a filler material and a saliva-permeable pouch made of packaging material enclosing the filler material, wherein the filler material contains a pH adjusting agent containing or consisting of the following: (i) Na₂CO₃, K₂CO₃, NaHCO₃ and/or KHCO₃ and (ii) salts of the following formula (I): M²⁺(A^n-)_m or a hydrate of said salt, wherein M²⁺ is selected from the group consisting of Ca²⁺, Mg²⁺, Mn²⁺, Zn²⁺ and Fe²⁺, A^n- is an anion, selected from the group consisting of chloride, lactate, malate, succinate, citrate, ascorbate, tartrate, acetate, phosphate, sulfate, nitrate, gluconate, alginate, ammonium, oxalate, aspartate, glycinate, picolinate, oxide, cysteinate, glutamate, hydroxide, laurate, stearate, palmitate, undecelinate, gluceptate, glucerophosphate, glubionate, glucoheptonate, guanylate, inosinate, propionate, sorbate, salicylate, benzoate, erythorbate, forata, iodide, pangamate and any combination thereof, n is 1 or 2, m is 1 or 2 and -(n×m)= -2. The specified salt is present in an amount from 0.1 to 5 wt.% based on the total weight of the filler material and has a water solubility equal to or greater than 0.04 M and/or equal to or greater than 1 g/L. The product also does not contain any tobacco material or contains it in small quantities, i.e. in the range from 0.05 to 10 wt.% based on the total weight of the filler material.

EFFECT: invention makes it possible to prevent, reduce and/or counteract changes in pH levels.

36 cl, 5 tbl, 3 ex, 3 dwg