USE OF PYRROLYLAZINES AS ACTIVATORS OF HEAT SHOCK PROTEIN SYNTHESIS Russian patent published in 2023 - IPC C07D403/04 A61K31/473 A61K31/506 A61K31/517 A61P25/28 

Abstract RU 2809487 C2

FIELD: chemistry; pharmaceuticals.

SUBSTANCE: invention relates to activators of the synthesis of heat shock proteins. The following is disclosed: the use of a compound selected from the group of 9-(5-hydroxy-1H-indol-3-yl)-10-methylacridinium iodide, 4-(5-bromo-1H-indol-3-yl)-2-chloropyrimidine, 4-(5-bromo-1H-indol-3-yl)quinazoline and 3-(5-phenyl-1H-pyrrol-2-yl)quinoxalin-2(1H)-one to activate the synthesis of heat shock proteins, as well as compound 9-(5-hydroxy-1H-indol-3-yl)-10-methylacridinium iodide and 4-(5-bromo-1H-indol-3-yl)quinazoline as activators of heat shock protein synthesis.

EFFECT: use of the invention makes it possible to effectively activate the synthesis of heat shock proteins.

3 cl, 8 dwg, 4 ex

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RU 2 809 487 C2

Authors

Lazarev Vladimir Fedorovich

Dutysheva Elizaveta Aleksandrovna

Trestsova Mariya Aleksandrovna

Mikhajlova Elena Radislavovna

Utepova Irina Aleksandrovna

Chupakhin Oleg Nikolaevich

Margulis Boris Aleksandrovich

Guzhova Irina Vladimirovna

Dates

2023-12-12Published

2020-10-30Filed