FIELD: medicine; medical technology.
SUBSTANCE: group of inventions relates to a method of applying an antimicrobial coating to a medical catheter and a protective polyurethane coating for a medical catheter. The method includes preparing the surface of a medical catheter before coating, preparing a polyurethane solution, preparing an antimicrobial solution by adding an antimicrobial agent to a polyurethane solution, forming a coating by immersing a medical catheter in an antimicrobial solution, then raising the catheter to ensure the solution flows over the surface, and drying the coating. The preparation of a polyurethane solution is carried out by dissolving it in tetrahydrofuran in quantities required to obtain a 5% polymer solution. Bicomponent Cu72/Fe28 nanoparticles with an average size of 72 nm with the structure of Janus nanoparticles are used as an antimicrobial agent, and the addition of an antimicrobial agent to a polyurethane solution is carried out by introducing bicomponent Cu72/Fe28 nanoparticles into the polyurethane solution in an amount of 7% by weight of the dry polymer with stirring and dispersing bicomponent Cu72/Fe28 nanoparticles in an ultrasonic bath for 30 minutes to obtain a homogenized suspension of nanoparticles, followed by evaporation of tetrahydrofuran. A protective polyurethane coating for a medical catheter, which has antimicrobial properties, contains at least 7% bicomponent Cu72/Fe28 nanoparticles by weight of the dry polymer.
EFFECT: protective coating on a medical catheter based on polyurethane and Cu/Fe nanoparticles, which has antimicrobial, antibacterial and antifungal properties while maintaining the flexibility, mobility and elasticity of the catheter.
6 cl, 5 dwg
Title | Year | Author | Number |
---|---|---|---|
ANTIBACTERIAL, ANTI VIRAL, ANTI FUNGAL PAINT MATERIALS | 2023 |
|
RU2807836C1 |
STEEL SHEET WITH ANTIMICROBIAL POLYMER COATING | 2022 |
|
RU2787282C1 |
POLYURETHANE CATHETER WITH ANTIMICROBIAL COATING, METHOD FOR PREPARING ANTIMICROBIAL COATING ON POLYURETHANE PRODUCTS AND METHOD FOR PRODUCING POLYURETHANE CATHETERS WITH ANTIMICROBIAL COATING | 2010 |
|
RU2457001C2 |
ANTIMICROBIAL COMPONENT AND METHOD FOR ITS PRODUCTION | 2022 |
|
RU2787382C1 |
SUPPORT WITH ELECTRON DONOR SURFACE, CONTAINING METALLIC PARTICLES INCLUDING PALLADIUM | 2007 |
|
RU2441672C2 |
POLYMER COATINGS CONTAINING COMPLEX OF IONIC FLUOROPOLYETHER AND COUNTER-IONIC AGENT | 2009 |
|
RU2470957C2 |
OBTAINING ANTIBACTERIAL Cu-Ti-O COATING BY EXTRACTION-PYROLYTIC METHOD | 2022 |
|
RU2801505C1 |
APPLICATION OF SUBSTRATE COATING TO REDUCE SUBSTANCE LEAKAGE | 2019 |
|
RU2805122C2 |
METHOD FOR MAKING ANTIMICROBIAL-COATED TUBULAR PRODUCTS, METHOD FOR PREPARING ANTIMICROBIAL COATING ON POLYURETHANE CATHETERS, PREFERENTIALLY MULTIPLE-LUMEN ONES, AND ANTIMICROBIAL-COATED MULTIPLE-LUMEN CATHETER | 2013 |
|
RU2531943C1 |
SUBSTANCE POSSESSING ANTIMICROBIAL ACTION | 2007 |
|
RU2473366C2 |
Authors
Dates
2023-12-27—Published
2022-12-21—Filed