FIELD: medicine.
SUBSTANCE: following is proposed: a method of intranasal administration of R4K2 KQLLPIVNKQSC peptide for the treatment of a respiratory viral infection caused by respiratory syncytial virus or influenza virus, where R is arginine; K is lysine; Q is glutamine, L is leucine, P is proline, I is isoleucine, V is valine, N is asparagine, S is serine, C is cysteine.
EFFECT: cationic branched R4K2 KQLLPIVNKQSC peptide blocks the entry of the virus into the cell both by binding to the cellular receptor nucleolin and by binding to ligands (F protein) on the surface of RSV.
1 cl, 13 dwg, 6 tbl, 8 ex
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Authors
Dates
2024-01-09—Published
2022-04-28—Filed