NK INVOLVING MOLECULES AND METHODS OF THEIR USE Russian patent published in 2024 - IPC C07K16/28 C07K16/46 C12N5/00 A61K35/17 

Abstract RU 2812481 C2

FIELD: biotechnology.

SUBSTANCE: following is described: a group of inventions including a compound for activating NK cells, a composition for use in inducing proliferation of NK cells, a method of inducing NK-mediated destruction of a target cell in a subject, a method of stimulating the proliferation of NK cells in vivo, a method of inhibiting the growth of cancer cells in a subject, a method of stimulating secretion of inflammatory cytokines by NK cells in vivo, and a method of treating acute myeloid leukemia (AML) in a subject.

EFFECT: invention expands the arsenal of means for activating NK cells.

26 cl, 53 dwg, 1 tbl, 11 ex

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RU 2 812 481 C2

Authors

Miller, Jeffrey, S.

Felices, Martin

Vallera, Daniel Attilio

Lenvik, Todd, R.

Dates

2024-01-30Published

2019-10-17Filed