FIELD: biotechnology.
SUBSTANCE: following is described: a group of inventions including a compound for activating NK cells, a composition for use in inducing proliferation of NK cells, a method of inducing NK-mediated destruction of a target cell in a subject, a method of stimulating the proliferation of NK cells in vivo, a method of inhibiting the growth of cancer cells in a subject, a method of stimulating secretion of inflammatory cytokines by NK cells in vivo, and a method of treating acute myeloid leukemia (AML) in a subject.
EFFECT: invention expands the arsenal of means for activating NK cells.
26 cl, 53 dwg, 1 tbl, 11 ex
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Authors
Dates
2024-01-30—Published
2019-10-17—Filed