FIELD: medicine; surgery; traumatology and orthopedics.
SUBSTANCE: invention can be used to replace osteomyelitic bone cavities. The antimicrobial composition for replacing bone cavities includes bone replacement material, vancomycin, high molecular weight hyaluronic acid in the form of a gel and Polymyxin B in the following component ratios, wt.%: 2.0–4.0 of high molecular weight hyaluronic acid; 1.0–1.5 of vancomycin; 1.5–2.5 of Polymyxin B; 95.5–92.0 of bone replacement material.
EFFECT: composition has an increased duration of antimicrobial action in the treatment of patients with chronic osteomyelitis, and also provides an antimicrobial effect against antibiotic-resistant microorganisms.
3 cl, 3 ex
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