METHOD OF DIFFERENTIATING ARRIAH-G333 GENOME OF GENETICALLY MODIFIED STRAIN FROM PB-97 VACCINE STRAIN OF RABIES VIRUS USING REAL-TIME POLYMERASE CHAIN REACTION WITH HIGH-RESOLUTION PEAK ANALYSIS Russian patent published in 2024 - IPC C12Q1/68 C12Q1/6876 C12Q1/6888 

Abstract RU 2812859 C1

FIELD: molecular biology.

SUBSTANCE: method of differentiating ARRIAH-G333 genome of genetically modified strain from RV-97 vaccine strain of the rabies virus using real-time polymerase chain reaction with analysis of high-resolution peaks with developed original oligonucleotide primers is described.

EFFECT: development of a sensitive and specific, rapid method for differentiating ARRIAH-G333 genome of genetically modified vaccine strain from RV-97 production strain using the polymerase chain reaction method in real time with high-resolution peak analysis.

2 cl, 2 dwg, 7 tbl, 4 ex

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RU 2 812 859 C1

Authors

Chupin Sergej Aleksandrovich

Doronin Maksim Igorevich

Mazlum Ali

Sprygin Aleksandr Vladimirovich

Dates

2024-02-05Published

2023-08-14Filed