CHIMERIC ENZYME BASED ON L-METHIONINE-GAMMA-LYASE FUSED WITH VHH ANTIBODY M456, AND DNA FRAGMENT CODING SAID ENZYME Russian patent published in 2024 - IPC C12N9/88 C07K16/28 C07K19/00 

Abstract RU 2813802 C1

FIELD: biotechnology.

SUBSTANCE: chimeric recombinant protein MGL-M456 for therapy of oncological diseases, consisting of L-methionine-gamma-lyase fused with VHH antibody BCD090-M456 is presented. Also disclosed is a genetic construct coding said chimeric protein.

EFFECT: group of inventions can be effectively used for therapy of oncological diseases.

2 cl, 2 dwg, 2 ex

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RU 2 813 802 C1

Authors

Bondarev Nikolaj Antonovich

Manukhov Ilya Vladimirovich

Buben Mariya Mikhajlovna

Bazhenov Sergej Vladimirovich

Dates

2024-02-19Published

2022-12-23Filed