FIELD: pharmacology.
SUBSTANCE: invention relates to the 5-(tetrahydrofuran-2-yl)-1,2,4-triazole-3-carboxylic acid amide having selective antiviral activity against influenza A virus and herpes simplex virus of the first type having the structural formula 
. The invention also relates to a process for amide preparation.
EFFECT: new compound with antiviral activity is obtained.
2 cl, 2 dwg, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| NEW 1-(-D-RIBOFURANOSIL-3-(5-SUBSTITUTED-1,2,4-OXADIAZOLE-3-YL)-1,2,4-TRIAZOLES WITH ANTI-VIRAL PROPERTIES AND METHOD FOR THEIR PRODUCTION | 2016 |
|
RU2629360C1 |
| 3-BUTYLTHIO-1-(BETA-D-2-DEOXYRIBOFURANOSYL)-5-PHENYL-(4H)-1,2,4-TRIAZOLE, SYNTHESIS, ANTI-HERPES VIRUS ACTION | 2023 |
|
RU2815137C1 |
| METHOD OF PRODUCING 5-SUBSTITUTED 1-H-1,2,4-TRIAZOLE-3-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | 2010 |
|
RU2446163C2 |
| 1-[ω-ARYLOXYALKYL(BENZYL)]-SUBSTITUTED 2-AMINOBENZIMIDAZOLES, HAVING ACTIVITY ON INFLUENZA VIRUS | 2012 |
|
RU2570906C2 |
| METHOD FOR PREPARING 1-β-D-RIBOFURANOSYL-1,2,4-TRIAZOLE-3-CARBOXAMIDE (RIB AVIRIN) | 2002 |
|
RU2230118C2 |
| NUCLEOSIDE ANALOGUES WITH CARBOXAMIDINE-MODIFIED MONOCYCLIC BASE | 2001 |
|
RU2259831C2 |
| METHOD FOR PREPARING 5-AMINO-1,2,4-TRIAZOL-3-YLCARBOXYLIC ACID AMIDES | 2005 |
|
RU2292339C1 |
| DERIVATIVES OF PYRAZINE AND THEIR SALTS, PHARMACEUTICAL COMPOSITION COMPRISING THESE COMPOUNDS | 2001 |
|
RU2259368C2 |
| -4-[6-(PURINE-6-YLAMINO)HEXANOYL]-3,4-DIHYDRO-3-METHYL-7,8-DIFLUOR-2H-[1,4]BENZOXAZINE AND (3R)-4-[6-(PURINE-6-YLAMINO)HEXANOYL]-3,4-DIHYDRO-3-METHYL-7,8-DIFLUOR-2H-[1,4]BENZOXAZINE WITH ANTIVIRAL ACTIVITY | 2016 |
|
RU2644351C1 |
| 2-AMINO-5,6-DIFLUOR-1-(BETA-D-RIBOFURANOSYL)-BENZIMIDAZOLE, METHOD FOR PRODUCTION AND ANTIVIRAL ACTIVITY IN TERMS OF HERPES SIMPLEX VIRUS TYPE I | 2016 |
|
RU2629670C2 |
