VITAMIN D DERIVATIVE CONTAINING CYCLIC AMINE IN SIDE CHAIN Russian patent published in 2024 - IPC C07D205/04 C07D207/12 C07D211/48 C07D241/04 C07D265/04 C07D295/26 A61K31/59 A61P9/00 A61P25/00

Abstract RU 2819389 C1

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to a vitamin D derivative of formula (1), a pharmaceutical composition, a remyelination stimulator, a therapeutic agent based thereon.

EFFECT: obtaining novel derivatives of vitamin D, having excellent migration into the central nervous system, which stimulate differentiation of oligodendrocyte precursor cells or nerve stem cells into oligodendrocytes and thereby stimulate myelin sheath regeneration.

22 cl, 11 tbl, 359 ex

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RU 2 819 389 C1

Authors

Saitoh, Hiroshi

Horie, Kyohei

Suga, Akiko

Kaibara, Yuya

Mashiko, Toshiya

Dates

2024-05-20—Published

2021-09-14—Filed