FIELD: chemistry.
SUBSTANCE: invention relates to biochemistry, in particular to a bivalent bispecific chimeric antibody, which includes a heterodimer based on juxtamembrane domains of MHC. Also disclosed is a method of producing said antibody.
EFFECT: invention enables to efficiently obtain bispecific antibodies.
60 cl, 14 tbl, 10 dwg, 12 ex
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|---|---|---|---|
| BISPECIFIC ANTIBODY AGAINST RABIES VIRUS AND ITS APPLICATION | 2019 |
|
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|
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| BISPECIFIC PROTEIN | 2019 |
|
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| ANTIBODIES SPECIFIC TO CD47 AND PD-L1 | 2020 |
|
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| TUMOR-TARGETING AGONIST CD28 ANTIGEN-BINDING MOLECULES | 2019 |
|
RU2837821C1 |
| ISOLATED ALTERNATIVE INTRACELLULAR SIGNALLING DOMAIN OF CHIMERIC ANTIGEN RECEPTOR AND CHIMERIC ANTIGEN RECEPTOR INCLUDING IT | 2019 |
|
RU2742000C2 |
| BISPECIFIC ANTIGEN-BINDING MOLECULES CONTAINING ANTI-FAP CLONE 212 | 2019 |
|
RU2799429C2 |
