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2 823 781

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IPC

C12Q1/68(2006-01-01)

C12Q1/6844(2018-01-01)

C12Q1/6876(2018-01-01)

(21) (22)

Application

2023128248, 2023-10-30

(24)

Start date

2023-10-30

(22)

Actual filing date

2023-10-30

(45)

Published

2024-07-30

(72)

Inventor

Doronin Maksim IgorevichMikhalishin Dmitrij ValerevichGalkina Tatyana SergeevnaChvala Ilya AleksandrovichBorisov Aleksej ValerevichZhbanova Tatyana ValentinovnaRazgulyaeva Evgeniya AleksandrovnaNegazina Nadezhda Nikolaevna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Tsentr Okhrany Zdorovya Zhivotnykh"

METHOD FOR INDIRECT DETERMINATION OF INFECTIOUS ACTIVITY TITRE OF CAUSATIVE AGENT OF INFECTIOUS FELINE RHINOTRACHEITIS IN RAW MATERIAL FOR VACCINE USING SECOND-ORDER DIFFERENTIAL OF POINT OF INTERSECTION OF LOGISTIC CURVE OF AMPLIFICATION REACTION OF UL35 GENE REGION Russian patent published in 2024 - IPC C12Q1/68 C12Q1/6844 C12Q1/6876

Abstract RU 2823781 C1

FIELD: biotechnology.

SUBSTANCE: described is a method for indirect determination of the titre of infectious activity of the causative agent of infectious feline rhinotracheitis in a raw material for a vaccine using a second-order differential of the point of intersection of the logistic curve of the amplification reaction of the UL35 gene region, which involves the use of the developed oligonucleotides.

EFFECT: developed method makes it possible to increase specificity of analysis, increase sensitivity and specificity of analysis, and also increase reliability of performed analysis.

2 cl, 2 dwg, 3 tbl, 4 ex

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RU 2 823 781 C1

Authors

Doronin Maksim Igorevich

Mikhalishin Dmitrij Valerevich

Galkina Tatyana Sergeevna

Chvala Ilya Aleksandrovich

Borisov Aleksej Valerevich

Zhbanova Tatyana Valentinovna

Razgulyaeva Evgeniya Aleksandrovna

Negazina Nadezhda Nikolaevna

Dates

2024-07-30—Published

2023-10-30—Filed