METHOD FOR ORAL DELIVERY OF CHEMICAL COMPOUNDS INTO FISH OF GENUS NOTHOBRANCHIUS FOR PRECLINICAL STUDIES Russian patent published in 2024 - IPC A01K61/00 A61K9/20 A61K36/02 

Abstract RU 2824822 C1

FIELD: experimental biology; medicine.

SUBSTANCE: invention relates to experimental biology and biomedicine and can be used in large-scale drug screening. Method involves preparing a solution of the active agent in the required concentration, combining and thoroughly mixing the solution of the active agent with an agar-agar carrier and an extract of Artemia salina nauplii. Moulding structure is made on 3D printer. Obtained pharmaceutical composition is applied on a moulding structure and thoroughly distributed on it. Pharmaceutical composition solidifies in the moulding structure at temperature of 4 °C. Obtained pastilles are extracted with the help of the puncheon forming part of the moulding structure. Dosed forms are transferred to the aquarium and fed to fish.

EFFECT: invention provides accurate doses of the active substance obtained by fish.

1 cl, 2 dwg, 1 ex

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Authors

Kudryavtseva Anna Viktorovna

Volodin Vsevolod Viktorovich

Aliper Gleb Mironovich

Bakhtogarimov Ildar Ramilevich

Goncharova Margarita Alekseevna

Dates

2024-08-14Published

2023-12-29Filed