METHOD FOR LOCALIZATION OF FOCAL EPILEPTOGENIC FOCUS DURING NEUROSURGICAL INTERVENTIONS Russian patent published in 2024 - IPC A61B5/55 A61B34/10 A61B34/20 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to neurosurgery, and can be used for resection of a focal epileptogenic focus. Surgical intervention is preceded by HARNESS magnetic resonance imaging (MRI) with 3D T2 FLAIR and 3D T1WI+CE sequences. Focal epileptogenic focus is located by 3D-reconstruction of cerebral structures relative to the adjacent sulci of the cerebral cortex, gyri of the cerebral cortex, superficial cerebral veins. MRI data are loaded into the Inobitec Pro program in DICOM format and sequential segmentation is performed: of the brain, sulci, cortex gyri of the area of interest, superficial cerebral veins of the area of interest and tissues of the focal epileptogenic focus, and a brain map with localization of the focal epileptogenic focus relative to adjacent sulci, gyri and superficial cerebral veins of the area of interest is obtained. Surgical entry point is determined on the obtained brain map. Incision and craniotomy zones are specified intraoperatively using a frameless navigation station. Soft tissues are incised, craniotomy is performed, and dura mater is opened. Intraoperative photograph of the naked cortex is obtained; the obtained photograph of the cortex is combined with a brain map; a surgical entry point is determined between the sulci, gyri of the cerebral cortex and superficial cerebral veins of the region of interest. Further, the boundaries and extent of the surgical resection of the focal epileptogenic focus are marked, and the focal epileptogenic focus is removed.

EFFECT: method provides more radical resection of the focal epileptogenic focus during the operation by increasing the accuracy of localizing the focal epileptogenic focus.

1 cl, 4 dwg, 3 ex