FIELD: medicine.
SUBSTANCE: invention relates to medicine, in particular to functional diagnostics, and can be used to determine endothelial dysfunction (hereinafter referred to as ED) in young women. A positive pressure exceeding systolic blood pressure is created in the shoulder area by means of a tonometer, and decompression is performed. Next, the peak systolic blood flow rate (PSS) is measured and the presence or absence of ED is determined. At the same time, a positive pressure is created that exceeds systolic blood pressure by 50 mmHg, and decompression is performed after 5 minutes. Using pulse-wave Doppler studies, the PSS is determined at 5 s, 10 s and 45 s after decompression and the fractions are determined The PSS at 10 and 45 seconds after decompression is from the maximum PSS corresponding to the value at 5 seconds after decompression. Diagnosis of endothelial dysfunction is carried out using previously obtained criteria, where the probability of the presence or absence of endothelial dysfunction is assessed. If the probability value is equal to or more than 0.5, the presence of endothelial dysfunction is diagnosed, and if the value is less than 0.5, the absence is diagnosed.
EFFECT: method makes it possible to effectively and quickly diagnose young women for the presence or absence of endothelial dysfunction by measuring the peak systolic blood flow rate.
1 cl, 1 dwg, 4 tbl, 3 ex
