FIELD: optics.
SUBSTANCE: invention relates to optics and concerns a method for producing an optical sensor with a plasmon structure for obtaining permitted spectra of the drug methotrexate in human plasma. Method involves chemical production of an island film of silver nanoparticles. For this purpose, a hydrosol of silver nanoparticles with size of up to 80 nm in amount of 2 ml is chemically deposited on chemically cleaned quartz glass of the “КУ-1” brand with size of 3 by 4 cm and then dried at room temperature for 2 hours.
EFFECT: simple design and enabling determination of the drug methotrexate in concentration of about 10-10 mol/l in human blood plasma.
2 cl, 2 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| OPTICAL SENSOR WITH A PLASMON STRUCTURE FOR DETERMINING LOW-CONCENTRATION CHEMICALS AND A METHOD FOR PRODUCTION THEREOF | 2019 |
|
RU2720075C1 |
| PLANAR NANOSTRUCTURED SENSOR BASED ON SURFACE PLASMON RESONANCE TO ENHANCE RAMAN LIGHT SCATTERING OF HUMAN PLATELETS AND METHOD FOR ITS PRODUCTION | 2022 |
|
RU2788479C1 |
| METHOD OF PRODUCING AMPLIFIED SIGNAL OF RAMAN LIGHT SCATTERING FROM HUMAN SERUM ALBUMIN MOLECULES IN LIQUID DROPLET | 2019 |
|
RU2708546C1 |
| METHOD FOR MEASURING THE CONCENTRATION OF POLYGLUTAMATES OF METHOTREXATE BY HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY WITH MASS SPECTROMETRIC DETECTION (HPLC-MS/MS) | 2020 |
|
RU2752805C1 |
| OPTICAL SENSOR FOR FLUORESCENCE QUENCHING OF OPTICALLY ACTIVE AMINO ACIDS IN PLATELETS AND METHOD FOR ITS PRODUCTION | 2022 |
|
RU2787689C1 |
| OPTICAL SENSOR WITH A PLASMONIC STRUCTURE FOR DETERMINING LOW CONCENTRATIONS OF FLUORESCENT AMINO ACIDS IN A PLATELET AND A METHOD FOR PRODUCING IT | 2022 |
|
RU2794993C1 |
| METHOD FOR PREDICTING EFFECTIVENESS OF TREATMENT OF RHEUMATOID ARTHRITIS WITH DRUG OLOKIZUMAB USING EPIGENETIC MARKERS | 2020 |
|
RU2749248C1 |
| STRUCTURE BASED ON PROTEIN PAIR OF BARNASE-BARSTAR AND METHOD OF ITS PRODUCTION | 2010 |
|
RU2480524C2 |
| PLANAR OPTICAL SENSOR FOR IDENTIFYING COMPONENTS OF THE CHEMICAL STRUCTURE OF BALTIC AMBER AND A METHOD OF ITS PRODUCTION | 2022 |
|
RU2797388C1 |
| METHOD FOR TUMOUR GROWTH INHIBITION IN EXPERIMENT | 2012 |
|
RU2506971C1 |
