CXCL8 INHIBITORS FOR USE IN TREATING COVID-19 Russian patent published in 2024 - IPC A61K31/18 A61K31/426 A61K31/167 A61K31/431 A61P31/14 A61P11/00 

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention relates to medicine and pharmaceutics, namely discloses the use of a CXCL8 inhibitor or a pharmaceutical composition containing a CXCL8 inhibitor and at least one inert pharmaceutically acceptable excipient, in treating a patient with pneumonia caused by COVID-19, wherein said CXCL8 inhibitor is a compound of formula (I) or a pharmaceutically acceptable salt thereof. In general formula (I), where R¹ is selected from linear or branched C1-C6 alkyl, benzoyl, phenoxy and trifluoromethanesulfonyloxy; R² is selected from a hydrogen atom and a linear or branched C1-C3 alkyl; and R³ is a linear or branched C1-C6 alkyl or trifluoromethyl. EFFECT: use of the invention enables the effective treatment of a patient with pneumonia caused by COVID-19.

11 cl, 1 dwg, 2 tbl, 2 ex