ANTIGEN RECEPTOR Russian patent published in 2024 - IPC C07K14/705 C07K14/725 A61K35/17 A61P35/00

Abstract RU 2832189 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, in particular to an antigen receptor containing a GITRL domain on the C-terminal side through a self-splitting peptide domain, as well as to a polynucleotide coding said antigen receptor. Also disclosed is a cell expressing said antigen receptor, wherein the cell is a T-cell with cytotoxic activity or NK-cell, and a pharmaceutical composition.

EFFECT: invention provides creation of antigen receptor with high therapeutic or preventive effect on cancer.

11 cl, 23 dwg, 12 ex

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RU 2 832 189 C2

Authors

Shiku, Hiroshi

Miwa, Hiroshi

Akahori, Yasushi

Fujiwara, Hiroshi

Dates

2024-12-23—Published

2020-07-31—Filed