FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing N-(2-aminoethyl)-3-benzoyl-4-hydroxy-1-(2-hydroxyphenyl)-2-(1H-indol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxamide of formula II by holding 3-benzoyl-2-hydroxy-3a-(1H-indol-3-yl)-1H-pyrrolo[2,1-c][1,4]benzoxazine-1,4(3aH)-dione formula I with ethylenediamine at room temperature according to the following scheme.
EFFECT: method for synthesis of N-(2-aminoethyl)-3-benzoyl-4-hydroxy-1-(2-hydroxyphenyl)-2-(1H-indol-3-yl)-5-oxo-2,5-dihydro-1H-pyrrole-2-carboxamide exhibiting anti-tuberculosis activity.
1 cl, 1 tbl, 1 ex
| Title |
Year |
Author |
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