FIELD: molecular biology.
SUBSTANCE: described is a composition for detecting colorectal cancer, containing reagents for determining the methylation status of the ADHFE1 gene, PPP2R5C gene and SDC2 gene, in which the reagents contain the developed oligonucleotides. Also described is a method for detecting a gene methylation status in a sample and a method for assessing the disease state of colorectal cancer in a subject for the purpose of diagnosing colorectal cancer using said composition.
EFFECT: development of a composition which can be used to detect colorectal cancer with high specificity and sensitivity, such that can facilitate clinical detection and expansion of the range of diagnostic tools and detection of colorectal cancer.
13 cl, 5 dwg, 4 tbl, 4 ex
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