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1 448 894

(13)

A1

(51)

IPC

(21) (22)

Application

4221847/14, 1987-04-03

(22)

Actual filing date

1987-04-03

(45)

Published

1994-01-30

(72)

Inventor

Ermolenko M.N.Pyshko E.S.Sviridov O.V.Strel'Chenok O.A.

METHOD FOR PURIFYING THYROID HORMONES LABELLED WITH 10D-125 Russian patent published in 1994 - IPC

Abstract SU 1448894 A1

FIELD: medicine. SUBSTANCE: gel of immunoaffined agent is added to preparation A (a reaction mixture comprising synthesized ([125I]T4) and is incubated at a temperature of 18-22 C for 2 hours. Suspension is washed in a microcolumn with alkaline water solution with pH= 11,0 until a disappearance of detectable radioactivity in the eluate is attained. The adsorbed [125I]T4 is eluated by 15-50% acetonitril solution acidulated to pH-value equal to 2.0-4.0. EFFECT: increased purity of finished product. 2 tbl

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SU 1 448 894 A1

Authors

Ermolenko M.N.

Pyshko E.S.

Sviridov O.V.

Strel'Chenok O.A.

Dates

1994-01-30—Published

1987-04-03—Filed

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