FIELD: organic chemistry. SUBSTANCE: product: derivatives of thiazolidine carboxylic acid amides of the general formula 
where R1 or R2 - hydrogen or pyridyl which is unsubstituted or C1-C4-substituted; R3 - hydrogen, C1-C4-alkyl, C1-C4-alkoxycarbonyl; R4 - hydrogen, C1-C4-alkyl; A - A-C2-C7-alkylene or alkylidene; Z - group 
, 
, 
, 
which can contain substituent C1-C4-alkyl at carbon atom of ring; R5 and R6 are similar or different and every - phenyl which can be substituted with halogen or halogen-C1-C4-alkyl, or unsubstituted aromatic 5- or 6-member heterocyclic group containing nitrogen or sulfur as heteroatom; E - bond or oxygen atom, or their pharmaceutically acceptable salts. Reagent 1: acid of the formula 
where R1-R3 as indicated above or its reactive derivative. Reagent 2: amine of the formula ZANHR4 where radical meanings were indicated above. Reaction conditions: removal of protecting group if necessary, isolation in the form of salt if it is required. Synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 11 cl, 3 tbl
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