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2 077 582

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C1

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IPC

(21) (22)

Application

94045159/13, 1994-12-29

(22)

Actual filing date

1994-12-29

(45)

Published

1997-04-20

(72)

Inventor

Romanova Ju.R.Aleksandrova G.I.Rudenko L.G.Klimov A.I.

(73)

Holder

Nauchno-Issledovatel'Skij Institut Ehksperimental'Noj Meditsiny Ramn

STRAIN A/17/SHANG-DONGH/93/3/5 (H3N2) FOR PRODUCTION OF LIVING INFLUENZA INTRANASAL VACCINE FOR ADULT Russian patent published in 1997 - IPC

Abstract RU 2077582 C1

FIELD: medicinal virology. SUBSTANCE: vaccine strain is obtained from the living intranasal vaccine for adult corresponding to actual virus A/Shang-Dongh/9/93 (H3N2) by antigenic properties. Vaccine strain-reassortant is obtained by crossing epidemic virus A/Shang-Dongh/9/93 (H3N2) with cold-adopted temperature-sensitive virus A/Leningrad/134/17/57 (H2N2) - attenuation donor that is harmless for adult and children. Strain is deposited in Collection GISK at N 132. Strain is actively multiplicated in developing chicken embryos. Strain A/17/Shang-Dongh/93/3/5 (H3N2) is nonreactive for adult (age is 18-20 years) at intranasal administration. EFFECT: preparing the strain indicated above. 1 tbl

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RU 2 077 582 C1

Authors

Romanova Ju.R.

Aleksandrova G.I.

Rudenko L.G.

Klimov A.I.

Dates

1997-04-20—Published

1994-12-29—Filed

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