RADIOPHARMACEUTICAL COMPOSITION AND METHODS OF ITS PREPARING Russian patent published in 1997 - IPC

Abstract RU 2095085 C1

FIELD: medicine, pharmacy. SUBSTANCE: composition has a complex of radionuclide 153-Sm or 166-Ho with ligand (ethylenediaminetetramethylene phosphonic acid) and bivalent metal salt that must be frozen. Composition is prepared by interaction of bivalent metal salt with a complex radionuclide - ligand followed by freezing. Other method involves addition of bivalent metal salt to ligand, medium pH correction and addition of the acidified radionuclide solution followed by freezing and thawing before the use. Composition has minimal ligand amount and does not require intravenous administration. EFFECT: enhanced effectiveness of composition. 8 cl, 10 tbl

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RU 2 095 085 C1

Authors

Dzhejm Simon[Us]

Dzhozef R.Garlich[Us]

R.Kit Frehnk[Us]

Kennet Makmillan[Us]

Dates

1997-11-10Published

1991-06-17Filed