FIELD: organic chemistry. SUBSTANCE: product: derivatives of nitroxyalkylamide of the general formula: R1-(A)n-CONH-B-ONO2 (I) where R1 - optionally substituted heterocyclic, hydroxy-heterocyclic, arylhydroxy or arylthio-group; A - C1-C4-alkylene group; B - C1-C4-alkylene group; n = 0 or 1. The compounds show effective vessel-dilating effect for collateral vessels and antistenocardia action and can be used as therapeutic agents for stenocardia treatment. EFFECT: improved method of synthesis, enhanced effectiveness of treatment. 44 cl, 2 tbl
Title |
Year |
Author |
Number |
OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVE, METHODS OF PREPARATION THEREOF, COMPOSITION FOR PROPHYLACTICS AND TREATMENT OF ANGINA PECTORIS, METHOD OF DILATION OF COLLATERAL VESSELS IN THE COURSE OF TREATMENT OR PROPHYLACTICS OF ANGINA PECTORIS, AND METHOD FOR TREATMENT AND PROPHYLACTICS OF ULCERATIVE DISEASE |
1996 |
- Sadao Isikhara
- Fudzio Saito
- Jasuzo Okhkhata
- Sigeki Mijake
- Riosuke Jorikane
- Norio Fukuda
- Kejti Tabata
- Mitsuko Makino
|
RU2141956C1 |
AMINO ACID DERIVATIVE AND METHOD OR PREPARATION THEREOF |
1992 |
- Sadao Isikhara[Jp]
- Fudzio Sajto[Jp]
- Takao Josioka[Jp]
- Khirojuki Koike[Jp]
- Sigeki Mijake[Jp]
- Khirosi Mizuno[Jp]
|
RU2104265C1 |
DERIVATIVES OF TETRAHYDROTHIENO-[3,2-C]-PYRIDINE OR THEIR FURO-ANALOGS AND A METHOD OF THEIR SYNTHESIS |
1992 |
- Koike Khirojuki[Jp]
- Fumitosi Asai[Jp]
- Atsukhiro Sugidati[Jp]
- Tomio Kimura[Jp]
- Terukhiko Inoue[Jp]
- Sigeesi Nisino[Jp]
- Jasunori Tsuzaki[Jp]
|
RU2089553C1 |
DERIVATIVES OF ISOXAZOLE AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
1997 |
- Kodzima Koiti
- Sakai Dzuniti
- Samata Naozumi
- Kozuka Masao
- Josimi Kendzi
- Kaneko Tsugio
|
RU2165415C2 |
ACYLATED HETEROALICYCLIC DERIVATIVES, MEDICINAL AGENT SHOWING SELECTIVE ANTAGONISTIC ACTIVITY AGAINST NK-RECEPTORS, METHOD OF PROPHYLAXIS OR TREATMENT OF PATIENTS |
1998 |
- Nisi Takakhide
- Jamaguti Takesi
|
RU2174122C1 |
IMIDAZOLE DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE ESTERS AND A METHOD OF THEIR SYNTHESIS |
1993 |
- Khiroaki Janagisava[Jp]
- Jasuo Simodzi[Jp]
- Esija Amemija[Jp]
- Takuro Kanazaki[Jp]
- Khirojuki Koike[Jp]
- Tosio Sada[Jp]
|
RU2086541C1 |
DERIVATIVE OF THIAZOLIDINONE SHOWING COLLATERAL-DILATATING ACTIVITY OF VESSEL, PHARMACEUTICAL COMPOSITION CONTAINING ON SAID FOR TREATMENT AND PROPHYLAXIS OF STENOCARDIA AND METHOD OF SYNTHESIS OF INDICATED THIAZOLIDINONE DERIVATIVES |
1995 |
- Sadao Isikhara
- Fudzio Saito
- Jasuo Okhkhata
- Sigeki Mijake
- Riosuke Jorikane
- Norio Fukuda
|
RU2139283C1 |
PEPTIDE COMPOUNDS AND METHOD OF PREPARING THEREOF |
1993 |
- Susumu Khigasida[Jp]
- Mitsujja Sakuraj[Jp]
- Jjutiro Jabe[Jp]
- Takasi Nisigaki[Jp]
- Tomoaki Komaj[Jp]
- Khirosi Khanda[Jp]
|
RU2106357C1 |
BIPHENYL DERIVATIVES AND METHOD OF PREPARING THEREOF |
1993 |
- Khiroaki Janagisava[Jp]
- Esija Amemija[Jp]
- Takuro Kanazaki[Jp]
- Jasuo Simodzi[Jp]
- Khirojuki Kojke[Jp]
- Tosio Sada[Jp]
|
RU2109736C1 |
DERIVATIVES OF 1,2-DIPHENYLPYRROLE, PHARMACEUTICAL COMPOSITION |
1997 |
- Tomio Kimura
- Jasuo Noguti
- Akira Nakao
- Kejsuke Suzuki
- Sigeru Usijama
- Akikhiro Kavara
- Masaaki Mijamoto
|
RU2125044C1 |