FIELD: pharmaceutical chemistry. SUBSTANCE: compound of general formula I: (I), wherein R1 is hydrogen atom, R2 C1-C6-alkyl, and n=1, is prepared by interaction of compound III: (III) or its reactive derivative with amine V: (V) or its acid-addition salt followed by nitration of interaction product. Optically active thiazolidinone derivative shows excellent activity against angina pectoris. EFFECT: increased prophylactic and therapeutic effects. 17 cl, 2 tbl, 29 ex
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Authors
Dates
1999-11-27—Published
1996-03-01—Filed