OPTICALLY ACTIVE THIAZOLIDINONE DERIVATIVE, METHODS OF PREPARATION THEREOF, COMPOSITION FOR PROPHYLACTICS AND TREATMENT OF ANGINA PECTORIS, METHOD OF DILATION OF COLLATERAL VESSELS IN THE COURSE OF TREATMENT OR PROPHYLACTICS OF ANGINA PECTORIS, AND METHOD FOR TREATMENT AND PROPHYLACTICS OF ULCERATIVE DISEASE Russian patent published in 1999 - IPC

Abstract RU 2141956 C1

FIELD: pharmaceutical chemistry. SUBSTANCE: compound of general formula I: (I), wherein R1 is hydrogen atom, R2 C1-C6-alkyl, and n=1, is prepared by interaction of compound III: (III) or its reactive derivative with amine V: (V) or its acid-addition salt followed by nitration of interaction product. Optically active thiazolidinone derivative shows excellent activity against angina pectoris. EFFECT: increased prophylactic and therapeutic effects. 17 cl, 2 tbl, 29 ex

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RU 2 141 956 C1

Authors

Sadao Isikhara

Fudzio Saito

Jasuzo Okhkhata

Sigeki Mijake

Riosuke Jorikane

Norio Fukuda

Kejti Tabata

Mitsuko Makino

Dates

1999-11-27Published

1996-03-01Filed