FIELD: pharmaceutical industry. SUBSTANCE: method of preparing compounds of formula (I) or (Ia) wherein R is 5-indanyl or group protecting carboxy group, or amine salts. Method comprises hydrogenation of (E)-allyl ether of formula (II) or (IIa), respectively, in the presence of stereoselective rhodium or ruthenium bisphosphine catalyst and protonic solvent to obtain enantiomers used to prepare drugs whose structural formulae are given below: 
. EFFECT: more efficient preparation method.
| Title |
Year |
Author |
Number |
| DERIVATIVES OF (AZETHIDINE-1-YLALKYL)-LACTAMES, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF TREATMENT OF HUMANS WHEN PATIENTS ARE TREATED BY PRODUCING ANTAGONISTIC EFFECT ON TACHYKININ ACTING IN HUMAN NK-, NK- AND NK-RECEPTORS OR IN THEIR COMBINATION |
1995 |
- Makenzi Aleksandr Roderik
- Marchington Alan Patrik
- Middlton Donal'D Stjuart
- Midouz Sandra Dora
|
RU2150468C1 |
| 3-AZETHIDINYLALKYLPIPERIDINES OR PYRROLIDINES AS TACHYKININE ANTAGONISTS, METHODS OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD OF TREATMENT |
1996 |
- Aleksandr Roderik Makkenzi
- Allan Patrik Marchington
- Donal'D Stjuart Middleton
- Sandra Dora Medous
|
RU2158264C2 |
| QUINOXALINE DERIVATIVES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION |
1995 |
- Majkl Dzhonatan Frej
- Charl'Z Ehrik Moubrej
- Alan Stoubi
|
RU2135484C1 |
| CRYSTALLINE POLYMORPHOUS FORM OF (S,S,S)-(N-(1-[2-CARBOXY-3- -N-MESYLLYSYLAMINO)PROPYL]-1-CYCLOPENTYLCARBONYL)TYROSINE, METHODS OF ITS SYNTHESIS, INTERMEDIATE COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHOD OF PATIENT TREATMENT |
1994 |
- Piter Dzhejms Dann
- Majkl Lesli Kh'Juz
|
RU2131869C1 |
| DERIVATIVES OF TRIAZOLE, METHODS OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT AND PROPHYLAXIS OF FUNGAL INFECTIONS, INTERMEDIATE COMPOUND |
1997 |
- Mertiashou Charlz V.
- Grin Stjuart
- Stefenson Piter T.
|
RU2176244C2 |
| METHOD OF SYNTHESIS OF TRIAZOLES, ULTIMATE AND INTERMEDIATE COMPOUNDS OF METHOD |
1996 |
- Majkl Batters
- Dzhuli Ehnn Kharrison
- Alan Dzhon Pettman
|
RU2156760C2 |
| DERIVATIVES OF OXA- OR THIADIZOLE, METHODS OF THEIR SYNTHESIS (VARIANTS), PHARMACEUTICAL COMPOSITION |
1997 |
- Aleksandr Roderik Makkenzi
- Ehntoni Vud
- Robert Dzhon Bass
|
RU2162848C2 |
| BENZOPYRANES, INTERMEDIATE COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHOD OF TREATMENT |
1994 |
- Aleksandr Roderik Makkenzi
- Sandra Marina Monagan
|
RU2122000C1 |
| (R)-(METHYLAMINOSULFONYLMETHYL)-3-(N-METHYLPYRROLIDINE-2-YL- -METHYL)-1H-INDOLE FUMARATE, METHOD OF ITS PREPARING, AGENT FOR TREATMENT OF MIRGAINE, PHARMACEUTICAL COMPOSITION FOR MIGRAINE TREATMENT |
1996 |
|
RU2161618C2 |
| METHOD OF ISOLATING R-(+)- AND S-(-)-AMPLODIPIN ISOMERS FROM MIXTURES THEREOF, (R)-(+) AND S-(-)-AMPLODIPIN-HEMI- L- OR D-TARTRATE SOLVATES AND MONOHYDRATES |
1995 |
|
RU2132845C1 |
