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2 118 366

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Application

96109409/13, 1996-05-06

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Actual filing date

1996-05-06

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Published

1998-08-27

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Inventor

Pikalova M.I.Domanova Z.M.Khajbullina I.I.Ostapenko E.V.Gorina G.I.Naumova N.V.Judina I.V.Kolokol'Tsov A.A.

(73)

Holder

Gosudarstvennyj Nauchnyj Tsentr Virusologii I Biotekhnologii

METHOD OF INDUSTRIAL PRODUCING THE HUMAN LEUKOCYTE INTERFERON-ALPHA-2 Russian patent published in 1998 - IPC

Abstract RU 2118366 C1

FIELD: biotechnology. SUBSTANCE: strain Escherichia coli SG 20050/pIF is grown on 2B-medium at the rate of rotating device 12-15 rev/min and aeration intensity 0.5-0.8 l/h. Polypeptide accumulation is (2.4-4.1) x 107 IU/ml. Method can be used for industrial production of the human recombinant interferon-alpha-2. EFFECT: improved method of producing, increased yield. 4 tbl, 4 ex

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RU 2 118 366 C1

Authors

Pikalova M.I.

Domanova Z.M.

Khajbullina I.I.

Ostapenko E.V.

Gorina G.I.

Naumova N.V.

Judina I.V.

Kolokol'Tsov A.A.

Dates

1998-08-27—Published

1996-05-06—Filed

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