FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes new derivatives of 1-benzene-sulfonyl-1,3-dihydro-2H-benzimidazole-2-one of the formula (I) where values R1-R3,R5 and R6, m are given in point 1 of the claim and pharmaceutical composition based on their. Compounds of the formula (I) show affinity to vasopressin and oxytocin receptors and can be used for treatment of patients with sicknesses of central and peripheral nervous systems, cardiovascular system, renal and gastric spheres and in sexual behavior disorders in human and animals. EFFECT: improved method of synthesis, enhanced effectiveness of compounds. 5 cl, 4 tbl, 116 ex
| Title |
Year |
Author |
Number |
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1994 |
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1996 |
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| SUBSTITUTED 3-ACYLAMINO-5-PHENYL-1,4-BENZODIAZEPIN 2-ONE DERIVATIVES, METHOD OF PREPARATION THEREOF, AND INTERMEDIATE PRODUCT |
1995 |
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1996 |
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1993 |
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- Didier Van Broek
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1996 |
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1993 |
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1994 |
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